Overall winner: SafeRest Premium Waterproof Mattress Protector, also consider Lucid L300 Waterproof Mattress Protector
When it comes to safeguarding your mattress, a waterproof protector is essential. We compared over 50 models, considering certifications like CertiPUR-US and OEKO-TEX, to find the top-rated options.
Based on owner reviews and specs, we ranked the best waterproof mattress protector sheets for you.

This protector features a 100% waterproof membrane, breathability, and a soft cotton top layer. It's machine washable and comes in a range of sizes. The fitted sheet design fits most standard mattress sizes.
Check current priceWe do not take payment for placement and we do not physically test products. Rankings come from manufacturer specifications, material certifications (CertiPUR-US foam, OEKO-TEX textiles), and the weight of aggregated verified owner reviews, analyzed for durability, heat retention and sagging. The scores in this guide are MattressVetted editorial research ratings — our assessment of the available evidence, not customer star averages. See how we rate.
Full method on our how we rate page.

back and stomach sleepers ·
This protector features a 100% waterproof membrane, breathability, and a soft cotton top layer. It's machine washable and comes in a range of sizes. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners praise its effectiveness in preventing stains and extending the lifespan of their mattress. Some mention that it runs a bit large.
stain-prone mattress owners ·
This protector features a waterproof layer and a soft, breathable mesh top. It's machine washable and comes in a variety of sizes. The elasticized corners ensure a secure fit.
What owners report: Owners appreciate its affordability and effectiveness in protecting their mattress from spills and stains. Some mention that it's not as breathable as other options.
This protector features a waterproof layer and a breathable, moisture-wicking top layer. It's designed to keep the mattress cool and dry. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners praise its ability to regulate temperature and prevent moisture buildup. Some mention that it can be a bit too thin.
This protector features a waterproof layer and a soft, breathable top layer. It's designed to provide pressure relief and comfort for side sleepers. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners appreciate its softness and pressure relief. Some mention that it can be a bit too thick for some mattresses.
This protector features a waterproof layer and a soft, breathable top layer. It's machine washable and comes in a range of sizes. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners praise its affordability and effectiveness in protecting their mattress. Some mention that it's not as breathable as other options.
firm mattress owners ·
This protector features a waterproof layer and a firm, breathable top layer. It's designed to provide support and pressure relief for firm mattress owners. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners appreciate its ability to retain firmness and provide pressure relief. Some mention that it can be a bit too rigid.
This protector features a waterproof layer and a breathable, hybrid top layer. It's designed to provide support and pressure relief for hybrid mattress owners. The fitted sheet design fits most standard mattress sizes.
What owners report: Owners praise its ability to regulate temperature and prevent moisture buildup. Some mention that it can be a bit too thick.
When shopping for a waterproof mattress protector, look for certifications like CertiPUR-US and OEKO-TEX, which ensure that the product meets safety and environmental standards.
It's recommended to wash your waterproof mattress protector every 3-6 months, or more often if you've experienced a spill or stain.
Most waterproof mattress protectors are compatible with standard mattress sizes, but it's best to check the manufacturer's recommendations for specific mattress types and sizes.
Some waterproof mattress protectors are designed to be breathable, while others may trap moisture. Look for products with breathable materials or moisture-wicking properties to ensure a comfortable sleeping experience.
It's generally recommended to air dry a waterproof mattress protector to prevent damage to the waterproof layer. However, some manufacturers may specify that their product can be machine dried; always follow the manufacturer's instructions.
Based on our research, the SafeRest Premium Waterproof Mattress Protector is our top pick for overall performance, offering a combination of waterproofing, breathability, and durability. For those on a budget, the Ettitude Waterproof Mattress Protector is a solid alternative. Additionally, the Protect-A-Bed Waterproof Mattress Protector is a great option for hot sleepers, while the Hush Soft Waterproof Mattress Protector is a good choice for side sleepers.