The Bissell ProHeat 2X Revolution Pet Pro is our top pick for its deep cleaning power and pet stain removal. For a budget-friendly option, the Hoover SmartWash Automatic is a reliable choice.
Keeping your mattress clean is essential for hygiene and longevity. After comparing over 30 products, we ranked the best mattress cleaners based on specs, certifications, and aggregated owner reviews from across the web.
Our research team evaluated cleaning performance, ease of use, and owner-reported satisfaction. We focused on products with proven stain removal, odor elimination, and safety certifications. The following picks represent the top contenders for 2026.
This carpet cleaner doubles as a mattress cleaner with its powerful spray and suction. Owners report it removes tough stains and pet odors effectively. The CleanShot pretreater targets problem areas before scrubbing.
Check current priceWe do not take payment for placement and we do not physically test products. Rankings come from manufacturer specifications, material certifications (CertiPUR-US foam, OEKO-TEX textiles), and the weight of aggregated verified owner reviews, analyzed for durability, heat retention and sagging. The scores in this guide are MattressVetted editorial research ratings — our assessment of the available evidence, not customer star averages. See how we rate.
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Pet owners and deep stain removal · Type: Upright cleaner | Firmness: N/A | Trial: 30-day return
This carpet cleaner doubles as a mattress cleaner with its powerful spray and suction. Owners report it removes tough stains and pet odors effectively. The CleanShot pretreater targets problem areas before scrubbing.
What owners report: Owners consistently praise its ability to revive stained mattresses and eliminate pet smells. Some note the machine is heavy but worth the effort.
Budget-conscious users needing automatic cleaning · Type: Upright cleaner | Firmness: N/A | Trial: 30-day return
This automatic carpet cleaner dispenses and removes solution without manual trigger. Owners love its easy operation and decent stain removal. It works well on mattress upholstery attachments.
What owners report: Owners appreciate the automatic function and affordable price. A few mention it can be noisy and leaves the mattress slightly damp.
Heavily soiled mattresses · Type: Upright cleaner | Firmness: N/A | Trial: 30-day return
The Rug Doctor offers professional-grade suction and brush action. Owners say it extracts more dirt than consumer models. Its large water tank reduces refills.
What owners report: Owners report impressive results on old stains and high-traffic mattress areas. Some find it heavy and expensive.

Spot cleaning and small jobs · Type: Portable spot cleaner | Firmness: N/A | Trial: 30-day return
This portable spot cleaner is ideal for targeted mattress stains. Owners like its portability and heat function. It's easy to store and use on furniture.
What owners report: Owners enjoy its convenience for quick spills and mattress spots. Some wish the hose were longer.
Allergy sufferers needing allergen removal · Type: Upright cleaner | Firmness: N/A | Trial: 30-day return
This cleaner comes with an allergen removal tool and HEPA filtration. Owners report reduced dust and allergens. It also includes a mattress tool.
What owners report: Owners with allergies notice less dust after cleaning. Some say the machine is a bit cumbersome.
Those who want a lightweight easy-to-use cleaner · Type: Portable spot cleaner | Firmness: N/A | Trial: 30-day return
Weighing under 10 pounds, the CleanSlate Plus is easy to maneuver. Owners like its portability for stairs and furniture. It effectively removes fresh stains.
What owners report: Owners appreciate the lightweight design and manual tools. A few note it's less powerful on set-in stains.
Those wanting a non-suction cleaning option · Type: Sonic cleaner | Firmness: N/A | Trial: 30-day return
This cleaner uses sonic scrubbing instead of suction. Owners like it for gentle cleaning on delicate fabrics. It's designed for carpets and hard floors with a mattress attachment.
What owners report: Owners find it effective for light cleaning and refreshing. Some dislike the lack of suction for wet messes.
Yes, most upright carpet cleaners have an upholstery attachment suitable for mattresses. Portable spot cleaners are also effective. Check the manual for mattress safety.
We recommend deep cleaning your mattress every 6-12 months, or more frequently if you have pets, allergies, or spills. Regular vacuuming between cleans helps.
Use a cleaner specifically labeled for upholstery or mattresses. Avoid harsh chemicals; many brands offer hypoallergenic and enzyme-based formulas that are safe.
Cleaning alone may not eliminate bed bugs. It can remove some, but professional treatment is usually required for infestations. Always check for signs of bed bugs first.
Drying time varies from 2-6 hours depending on humidity and airflow. Use fans or open windows to speed up drying. Avoid using until completely dry to prevent mold.
The Bissell ProHeat 2X Revolution Pet Pro is our best overall for its powerful cleaning and pet stain abilities. For budget-conscious shoppers, the Hoover SmartWash Automatic offers great value with automatic dispensing. If you need an easy portable option for spot cleaning, the Bissell SpotClean ProHeat is a solid choice.